BDBM451831 US10710980, Example 60::US10947218, Example 60

SMILES CC#CCN1C[C@H]2C[C@]2(C1)c1ccc(cc1)-c1cnc(N)c(c1)C(=O)N[C@H]1CC[C@H](O)CC1

InChI Key InChIKey=BBWFHMVFMVFXJP-ANAFOTAVSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 451831   

TargetActivin receptor type-1 [172-499,R206H](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451831(US10710980, Example 60 | US10947218, Example 60)
Affinity DataIC50:  19nMAssay Description:In the applied method, this separation takes place inside a chip that contains a complex capillary system for simultaneous analysis of 12 samples (“1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetActivin receptor type-1 [172-499,R206H](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451831(US10710980, Example 60 | US10947218, Example 60)
Affinity DataIC50:  19nMAssay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for wild-type ALK2 (aa172-499), ALK2 FOP mutant (aa172-499 R20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent